Formulation & Suspensions

Pharmaceuticals & Biotech Sector
Formulation & Suspensions represent a critical branch of the pharmaceutical and chemical industries, focusing on the stability and performance of liquid and semi-liquid systems. Su...

Industry Overview

Formulation & Suspensions represent a critical branch of the pharmaceutical and chemical industries, focusing on the stability and performance of liquid and semi-liquid systems. Suspensions are heterogeneous mixtures where solid particles are dispersed in a liquid medium. Their stability determines product quality, shelf life, and therapeutic effectiveness. DataPhysics Instruments provide advanced analytical tools to evaluate dispersion stability, zeta potential, and interfacial properties, enabling scientists and engineers to design formulations that remain stable, effective, and safe under real-world conditions.

Key Features

Suspensions are widely used in pharmaceuticals, food, cosmetics, and specialty chemicals. In pharmaceuticals, suspensions deliver poorly soluble drugs in liquid form, improving bioavailability and patient compliance. In food, suspensions appear in products like juices, sauces, and dairy drinks. In cosmetics, they are found in creams and lotions.
The challenge lies in maintaining stability. Suspensions tend to separate over time due to sedimentation, flocculation, or coalescence. Stability depends on particle size, surface charge, viscosity of the medium, and interactions between particles.
DataPhysics Instruments address these challenges with precision. The ZPA 20 (Zeta Potential Analyzer) measures particle surface charge, a key indicator of dispersion stability. High zeta potential values suggest strong repulsion between particles, preventing aggregation. The MultiScan system monitors suspensions over time, detecting early signs of instability such as creaming or sedimentation. The DCAT tensiometer measures interfacial tension, helping formulators understand how particles interact with the liquid medium.
In R&D, these tools allow scientists to optimize formulations by adjusting stabilizers, surfactants, and particle size. In production, they support quality assurance by providing reproducible, automated measurements that ensure batch-to-batch consistency.
Suspensions are not just mixtures—they are engineered systems requiring precise control of interfacial and colloidal properties. DataPhysics Instruments empower formulators to achieve this control, driving innovation and reliability across industries.

Typical Tests & Applications

Key tests for Formulation & Suspensions include:
- Zeta Potential Measurement (ZPA 20)
- Purpose: Assess particle surface charge.
- Application: Predict stability and prevent aggregation.
- Benefit: Optimize stabilizer and surfactant use.
- Dispersion Stability Monitoring (MultiScan)
- Purpose: Track suspension behavior over time.
- Application: Detect sedimentation, creaming, or flocculation.
- Benefit: Ensure long shelf life and product reliability.
- Interfacial Tension Measurement (DCAT)
- Purpose: Evaluate particle-liquid interactions.
- Application: Optimize formulation compatibility.
- Benefit: Improve dispersion uniformity.
- Dynamic Contact Angle Analysis (OCA, DCAT)
- Purpose: Study wetting of particles in liquid.
- Application: Enhance particle dispersion.
- Benefit: Reduce clumping and improve performance.
- Environmental Simulation (HGC)
- Purpose: Test stability under humidity changes.
- Application: Validate real-world performance.
- Benefit: Ensure consistent product quality.
These tests provide formulators with actionable data to design stable, effective suspensions across pharmaceuticals, food, and cosmetics.

Industry Resources

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Supporting Products

DCAT – Dynamic Contact Angle measuring devices and Tensiometer Contact Angle & Surface Tension

DCAT – Dynamic Contact Angle measuring devices and Tensiometer

Part #: DCAT

The versatile DCAT Series combines dynamic contact angle measuring devices and force tensiometers to...

MS – MultiScan dispersion stability analysis system Contact Angle & Surface Tension

MS – MultiScan dispersion stability analysis system

Part #: MS

The MultiScan MS 20 is an advanced optical analyzer designed for automatic, time- and temperature-...

ZPA – Zeta Potential Analyzer Contact Angle & Surface Tension

ZPA – Zeta Potential Analyzer

Part #: ZPA

The ZPA 20 is a compact, high-precision instrument that measures surface zeta potential of macrosc...

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