Biopharma

Pharmaceuticals & Biotech Sector
Biopharma focuses on biologically derived products such as proteins, antibodies, vaccines, and cell-based therapies. These products are highly sensitive to environmental conditions...

Industry Overview

Biopharma focuses on biologically derived products such as proteins, antibodies, vaccines, and cell-based therapies. These products are highly sensitive to environmental conditions and require precise control of colloidal stability, surface interactions, and formulation properties. DataPhysics Instruments provide advanced tools to measure zeta potential, dispersion stability, and interfacial tension, enabling biopharma companies to ensure product safety, efficacy, and consistency from research through production.

Key Features

Biopharmaceuticals are revolutionizing healthcare, offering targeted therapies for cancer, autoimmune diseases, and infectious conditions. Unlike traditional small-molecule drugs, biopharma products are complex macromolecules or living cells. Their stability and functionality depend on delicate interactions at the molecular and colloidal level.
Proteins, for example, can aggregate if their surface charge is insufficient to maintain repulsion. Aggregation reduces efficacy and may trigger immune responses. Vaccines require stable suspensions of antigens to remain effective during storage and transport. Cell-based therapies demand precise control of culture media and surface interactions.
DataPhysics Instruments provide tools to address these challenges. The ZPA 20 measures zeta potential, helping researchers understand protein stability and aggregation risks. The MultiScan system monitors dispersion stability, detecting early signs of destabilization in protein solutions or vaccine suspensions. The DCAT tensiometer evaluates interfacial tension, offering insights into how proteins interact with excipients or surfaces.
In R&D, these tools support formulation optimization, ensuring biopharma products remain stable and effective. In production, they provide quality assurance by delivering reproducible, automated measurements that comply with regulatory standards.
Biopharma is not just about producing drugs—it is about engineering complex biological systems that require precise control of interfacial and colloidal properties. DataPhysics Instruments empower researchers and manufacturers to achieve this control, driving innovation and patient safety.

Typical Tests & Applications

Key tests for Biopharma include:
- Zeta Potential Measurement (ZPA 20)
- Purpose: Assess protein and colloid stability.
- Application: Prevent aggregation and immune reactions.
- Benefit: Ensure therapeutic efficacy.
- Dispersion Stability Monitoring (MultiScan)
- Purpose: Track protein solutions and vaccine suspensions.
- Application: Detect destabilization early.
- Benefit: Extend shelf life and reliability.
- Interfacial Tension Measurement (DCAT)
- Purpose: Study protein-excipient interactions.
- Application: Optimize formulations.
- Benefit: Improve stability and performance.
- Dynamic Contact Angle Analysis (OCA, DCAT)
- Purpose: Evaluate protein adsorption on surfaces.
- Application: Prevent fouling and loss of activity.
- Benefit: Enhance bioprocess efficiency.
- Environmental Simulation (HGC)
- Purpose: Test stability under humidity and temperature changes.
- Application: Validate storage and transport conditions.
- Benefit: Ensure product safety and compliance.
These tests provide biopharma companies with the precision and insight needed to design safe, effective, and reliable biological therapies.

Industry Resources

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Supporting Products

DCAT – Dynamic Contact Angle measuring devices and Tensiometer Contact Angle & Surface Tension

DCAT – Dynamic Contact Angle measuring devices and Tensiometer

Part #: DCAT

The versatile DCAT Series combines dynamic contact angle measuring devices and force tensiometers to...

MS – MultiScan dispersion stability analysis system Contact Angle & Surface Tension

MS – MultiScan dispersion stability analysis system

Part #: MS

The MultiScan MS 20 is an advanced optical analyzer designed for automatic, time- and temperature-...

ZPA – Zeta Potential Analyzer Contact Angle & Surface Tension

ZPA – Zeta Potential Analyzer

Part #: ZPA

The ZPA 20 is a compact, high-precision instrument that measures surface zeta potential of macrosc...

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