Biofarmasi
Farmasi & Bioteknologi Sektor
Biofarma berfokus pada produk yang berasal dari biologi seperti protein, antibodi, vaksin, dan terapi berbasis sel. Produk-produk ini sangat sensitif terhadap kondisi lingkungan da...
Ikhtisar Industri
Biofarma berfokus pada produk yang berasal dari biologi seperti protein, antibodi, vaksin, dan terapi berbasis sel. Produk-produk ini sangat sensitif terhadap kondisi lingkungan dan memerlukan kontrol presisi terhadap stabilitas koloid, interaksi permukaan, dan sifat formulasi.
Fitur Utama
Biopharmaceuticals are revolutionizing healthcare, offering targeted therapies for cancer, autoimmune diseases, and infectious conditions. Unlike traditional small-molecule drugs, biopharma products are complex macromolecules or living cells. Their stability and functionality depend on delicate interactions at the molecular and colloidal level.
Proteins, for example, can aggregate if their surface charge is insufficient to maintain repulsion. Aggregation reduces efficacy and may trigger immune responses. Vaccines require stable suspensions of antigens to remain effective during storage and transport. Cell-based therapies demand precise control of culture media and surface interactions.
DataPhysics Instruments provide tools to address these challenges. The ZPA 20 measures zeta potential, helping researchers understand protein stability and aggregation risks. The MultiScan system monitors dispersion stability, detecting early signs of destabilization in protein solutions or vaccine suspensions. The DCAT tensiometer evaluates interfacial tension, offering insights into how proteins interact with excipients or surfaces.
In R&D, these tools support formulation optimization, ensuring biopharma products remain stable and effective. In production, they provide quality assurance by delivering reproducible, automated measurements that comply with regulatory standards.
Biopharma is not just about producing drugs—it is about engineering complex biological systems that require precise control of interfacial and colloidal properties. DataPhysics Instruments empower researchers and manufacturers to achieve this control, driving innovation and patient safety.
Proteins, for example, can aggregate if their surface charge is insufficient to maintain repulsion. Aggregation reduces efficacy and may trigger immune responses. Vaccines require stable suspensions of antigens to remain effective during storage and transport. Cell-based therapies demand precise control of culture media and surface interactions.
DataPhysics Instruments provide tools to address these challenges. The ZPA 20 measures zeta potential, helping researchers understand protein stability and aggregation risks. The MultiScan system monitors dispersion stability, detecting early signs of destabilization in protein solutions or vaccine suspensions. The DCAT tensiometer evaluates interfacial tension, offering insights into how proteins interact with excipients or surfaces.
In R&D, these tools support formulation optimization, ensuring biopharma products remain stable and effective. In production, they provide quality assurance by delivering reproducible, automated measurements that comply with regulatory standards.
Biopharma is not just about producing drugs—it is about engineering complex biological systems that require precise control of interfacial and colloidal properties. DataPhysics Instruments empower researchers and manufacturers to achieve this control, driving innovation and patient safety.
Tes & Aplikasi Khas
Key tests for Biopharma include:
- Zeta Potential Measurement (ZPA 20)
- Purpose: Assess protein and colloid stability.
- Application: Prevent aggregation and immune reactions.
- Benefit: Ensure therapeutic efficacy.
- Dispersion Stability Monitoring (MultiScan)
- Purpose: Track protein solutions and vaccine suspensions.
- Application: Detect destabilization early.
- Benefit: Extend shelf life and reliability.
- Interfacial Tension Measurement (DCAT)
- Purpose: Study protein-excipient interactions.
- Application: Optimize formulations.
- Benefit: Improve stability and performance.
- Dynamic Contact Angle Analysis (OCA, DCAT)
- Purpose: Evaluate protein adsorption on surfaces.
- Application: Prevent fouling and loss of activity.
- Benefit: Enhance bioprocess efficiency.
- Environmental Simulation (HGC)
- Purpose: Test stability under humidity and temperature changes.
- Application: Validate storage and transport conditions.
- Benefit: Ensure product safety and compliance.
These tests provide biopharma companies with the precision and insight needed to design safe, effective, and reliable biological therapies.
- Zeta Potential Measurement (ZPA 20)
- Purpose: Assess protein and colloid stability.
- Application: Prevent aggregation and immune reactions.
- Benefit: Ensure therapeutic efficacy.
- Dispersion Stability Monitoring (MultiScan)
- Purpose: Track protein solutions and vaccine suspensions.
- Application: Detect destabilization early.
- Benefit: Extend shelf life and reliability.
- Interfacial Tension Measurement (DCAT)
- Purpose: Study protein-excipient interactions.
- Application: Optimize formulations.
- Benefit: Improve stability and performance.
- Dynamic Contact Angle Analysis (OCA, DCAT)
- Purpose: Evaluate protein adsorption on surfaces.
- Application: Prevent fouling and loss of activity.
- Benefit: Enhance bioprocess efficiency.
- Environmental Simulation (HGC)
- Purpose: Test stability under humidity and temperature changes.
- Application: Validate storage and transport conditions.
- Benefit: Ensure product safety and compliance.
These tests provide biopharma companies with the precision and insight needed to design safe, effective, and reliable biological therapies.
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Minta DokumentasiProduk Pendukung
Contact Angle & Surface Tension
DCAT – Alat Ukur Sudut Kontak Dinamis dan Tensiometer
Nomor Bagian: DCAT
Seri DCAT menggabungkan perangkat pengukur sudut kontak dinamis dan tensiometer gaya untuk mengevalu...
Contact Angle & Surface Tension
MS – Sistem Analisis Stabilitas Dispersi MultiScan
Nomor Bagian: MS
MultiScan MS 20 adalah penganalisis optik canggih yang dirancang untuk analisis stabilitas dan penua...
Contact Angle & Surface Tension
ZPA – Penganalisis Potensial Zeta
Nomor Bagian: ZPA
ZPA 20 adalah instrumen ringkas yang mengukur potensi zeta permukaan sampel padat makroskopik dalam ...
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